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Description
TGR5-mediated bile acid sensing controls glucose homeostasis
doi: 10.1007/978-3-662-41088-2_14 110 WangXSharmaRKGuptaAGeorgeVThomasAJJr.FalconeTet al
When this happens, and additionally infection by SARS-CoV-2 downregulates ACE2 abundance on cell surfaces, as suggested by evidence from related coronaviruses [2], the result is the toxic overaccumulation of ANGII, exacerbated inflammation and, finally, acute respiratory distress syndrome and fulminant myocarditis (Figure 1)
The primary completion date is February 2027
doi:10.1371/journal.pone.0145453
