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Front Physiol (2017) 8:350

Treatment and medication history should be thoroughly reviewed, including prescribed drugs, over-the-counter medications, and culturally approved aphrodisiacs [50]

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Moreover, two separate markers of oxidative stress, anti-nitrotyrosine and anti-4-HNE immunostaining, were also found to be elevated only in the glomerulus of Pdss2 kd/kd mice where tissue damage occurs (124)

Specifically, they observed that the HPT-to-creatinine ratio (HCR) is a strong independent predictor of eGFR decline, demonstrating greater sensitivity and specificity than the commonly used ACR