copper uglies reddit ghk cu PSA] Finally, a Dr. explains the mechanism behind the "copper uglies" : r/SkincareAddiction I've finally hit the copper
Description
PE-22-28 (Mini-Spadin) blocks TREK-1 potassium channels with ~100-fold greater potency than its parent compound, demonstrating BDNF upregulation, rapid neurogenesis within 4 days, and cognitive benefits in stroke models (Djillani et al., 2017 in Frontiers in Pharmacology)
The choice comes down to personal preference regarding convenience versus flexibility and cost
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Consult primary literature for compound-specific findings
2004;287:G676G684
Comparing them is more useful for understanding the evidence hierarchy in drug development than for choosing between two equivalent options
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