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The coelomic cavity is now believed to be an important transfer interface for the embryo, present very early in gestation (Cumano and Godin, Ethical Considerations IUSCT is ultimately performed on two patients: the mother and her fetus

insulin pump day 1 by Erin Stevenson OConnor is licensed under CC BY-SA 2.0

A recent study found that co-administration of Rapamycin-loaded poly(lactic acid) (PLA) nanoparticles (SVP(Rapa)) with AAV vectors prevents the formation of neutralizing antibodies and enables successful vector re-administration in mice and nonhuman primates in an antigen selective manner, in addition to allowing for repeat dosing of AAV vectors to increase expression of a transgene in the liver

doi: 10.1016/j.semcdb.2017.05.023

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