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Three trials were conducted in men (Reference Lecoultre, Carrel and Egli32,Reference Ohnaka, Ikeda and Maki38,Reference Superko, Bortz and Williams40) , three in women (Reference Ahmed Al-Naggar, Osman and Abdulghani23,Reference Cardoso, Salgado and Cesar28,Reference Mortazavi, Paknahad and Hasanzadeh34) and the remainder in either sex

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First, the extracellular facing -glutamyl transpeptidase (GGT) protein cleaves the -glutamyl bond of glutathione and liberates the -glutamyl amino acid from the cysteinylglycine dipeptide