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In addition, noise trauma could induce elevate mitochondrial calcium levels and metabolic demand in hair cells, subsequently increasing ROS production (Henderson et al., 2006
[DOI] [PubMed] [Google Scholar] 73.Ledeboer A., Jekich B.M., Sloane E.M., Mahoney J.H., Langer S.J., Milligan E.D., Martin D., Maier S.F., Johnson K.W., Leinwand L.A., Chavez R.A., Watkins L.R

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Both excesses and deficiencies of certain nutrients, as well as exposure to heavy metals, toxins, and endocrine disruptors, can disrupt immune tolerance
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