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Testosterone: a metabolic hormone in health and disease

doi: 10.1073/pnas.1002213107

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This self-reinforcing feedback loop involving diet, microbiome, and intestinal health via the redox state is reflected in recent studies showing that fiber prebiotics significantly reduced the impact of antibiotic treatment on microbiome's composition and function via modulation of the gut redox potential

The discrepancies between these studies stem from differences in age, the period of risk analyzed (start of treatment or maintenance of treatment), and the way in which confounding factors (cardiovascular history, smoking) were controlled