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The resulting diminishment of Hes1 expression and other Notch effectors compromises the sphere-forming ability of CSCs and their capacity to maintain the undifferentiated state (72, 73)
Rudman D
This is the first clinical-grade safety signal in humans
At the same time, risk of hyperpigmentation was noted to be higher in those groups treated with copper peptide compared to the group treated with plain dermaroller
Huang et al., 2006
