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Because of lack of renal clearance, serum values rose to more than a hundredfold from 422 pmol/L on average to 54 000 pmol/L, with 67 000 pmol/L as highest value, without side-effects

in the 100 mg dose present here, serious GI effects are uncommon, but mild nausea or stomach discomfort could occur in sensitive patients

A study of comprehensive structureactivity relationships (SARs) revealed that quinolinium analogues inhibit NNMT at low concentrations and selectively bind to the NNMT substrate-binding site residues (99)

I have been totally intolerant of simvastatin, atorvastatin and some other statin I cannot remember

Ding, X., Kakanj, P., Leptin, M., & Eming, S