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[DOI] [PMC free article] [PubMed] [Google Scholar] 100.Xu W, Wang X, Tocker AM, Huang P, Reith ME, Liu-Chen LY, Smith Iii AB, Kortagere S

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doi: 10.1016/j.smallrumres.2021.106443 168

In humans, histopathological examination of temporal bone specimens from patients who received cisplatin revealed a significant loss of IHCs and OHCs, atrophy of the stria vascularis, and decreased SGNs in the basal turn of the cochlea 67

In certain contexts, they can transition into severe reactive astrocytes, often characterized by proliferative changes and markers such as monoamine oxidase B (MAO-B) and GFAP upregulation
