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DOPA pheomelanin is increased in nigral neuromelanin of parkinsons disease

J Environ Sci Health C Toxicol Carcinog 39:6886

Moreover, imbalanced Mn levels may contribute to the pathogenesis of other neurological disorders, such as Huntingtons disease (HD), attention-deficit/hyperactivity disorder (ADHD), and Alzheimers disease (AD)

It is the biological catalyst responsible for converting testosterone into dihydrotestosterone (DHT), the potent androgen blamed for male pattern baldness, acne, and prostate enlargement