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To confirm that the improved response to cold was dependent on creatine, mice were treated with the creatine-depleting drug -guanidinopropionic acid (-GPA) 21 , which can only be used acutely as chronic exposure can induce weight loss 19,21

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Table 4 Associations between genetic polymorphisms and plasma MTX level at 48 h

[DOI] [PMC free article] [PubMed] [Google Scholar] 261.Fuse Y., Kobayashi M

FIGURE 3 Vitamin B12 Inhibited Microtubule Damage Through ER Stress After TBI Numerous studies have indicated that vitamin B12 has neuroprotective effects on TBI (Sun et al., 2012