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While the immediate consequence of amplification of mitochondrial oxidant stress is loss of mitochondrial protein function due to modification of thiols [33], peroxynitrite mediated nitrotyrosine formation [48] and oxidative mitochondrial DNA damage [41], the critical event resulting in escalation of cell wide damage is induction of the mitochondrial permeability transition (MPT)

doi: 10.1111/j.1365-3040.2011.02338.x

Who Should Consider B-12 Injections in Alpharetta, Atlanta, Suwanee, and Braselton

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