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Yang Y, An Y, Ren M, et al

This substrate functions as an inhibitor of the enzyme succinate dehydrogenase, promotes succinate accumulation, stabilizes HIF-1, and decreases mitochondrial respiration, leading to more ROS

Front Pharmacol (2022) 13
Melatonin was also found to have an impact on stem cell differentiation

Epidemiology of AKI: Utilizing large databases to determine the burden of AKI
