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By inducing ROS accumulation, modulating mitochondrial membrane potential, and activating oxidative stress-related pathways, the nanozyme suppresses tumor proliferation and restores sensitivity to chemotherapeutic agents such as 5-FU [101]

Regulation of iron homeostasis by hepatocyte TfR1 requires HFE and contributes to hepcidin suppression in -thalassemia

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Halogenated alkenes, hydroquinones, and quinones have been shown to form toxic metabolites via the formation of S-conjugates with GSH