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For example, while use of a relatively low overdose of 200 mg/kg APAP demonstrated protection against liver injury in cyclophilin D-deficient mice [96], only transient protection was achieved when cyclophilin was inhibited using cyclosporine A in vitro [94]

Biochim Biophys Acta 1830:32173266

Terpenoids Terpenoids are natural compounds with a wide distribution, great variety, and diversified structure in nature [140]

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Caspase recruitment domain protein 6 protects against hepatic steatosis and insulin resistance by suppressing Ask1