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Description
An enzyme called Carnitine Palmitoyltransferase I (CPT1), located on the outer mitochondrial membrane, attaches a molecule of L-carnitine to the long-chain fatty acid, creating an acylcarnitine complex
Acylcarnitine subsequently increases the activity of mitochondrial electron transport chain complexes and mitochondrial OXPHOS by promoting the acetylation of H3K27

Actual Size Expert Opin Drug Metab Toxicol

doi: 10.1021/bi00321a022

During Salmonella Typhimurium infection, C16-carnitine localizes to regions of immune cell destruction, and C16-carnitine acts as a local immunoregulatory molecule that significantly interferes with host immune homeostasis by affecting the number and function of specific immune cell populations, such as T cells and B cells, suggesting that the accumulation of LCACs is part of the pathogen immune evasion strategy [60]
