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doi: 10.1155/2014/807874

Among them, celecoxib (a 1,5-diarylpyrazole compound), the first COX-2-specific inhibitor used to inhibit tumor apoptosis, proliferation, angiogenesis, and metastasis (Masferrer et al., 2000

Such compounds might include neutrophil-generated species such as hypochlorous acid (HOCl), hypothiocyanous acid (HOSCN), and nitric oxide (NO)

At least 5 independent replicates of each compound were maintained up to 25 freeze-thaw cycles, with a minimum of 3 freezing points for each replicate

For this reason, verapamil is considered to be the most dangerous of the CCBs, although any of them can cause death in overdose