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Studies have shown that microglia originate from embryonic yolk sac progenitors during early development, are of primitive hematopoietic origin, and persist into adulthood, maintaining independence from bone marrow-derived myeloid cells throughout life, shaping their distinct functions across maturation and aging (Ginhoux et al., 2013

Acta 614 , 8191 (1980)

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OXI1 kinase is necessary for oxidative burst-mediated signalling in Arabidopsis