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Duems-Noriega O, Ario-Blasco S

Administration differs between the two peptides
The MHRA recommends monitoring B12 levels in patients on long-term metformin treatment

Lower NAD+ means reduced sirtuin activity (SIRT1, SIRT3), which further impairs mitochondrial function and fatty acid oxidation in fat cells

Some patients may experience mild redness, swelling, or pain at the injection site, but these symptoms usually subside within a few hours
