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9, A, fluorescently labeled free-DNAzymes could rarely appear inside the brain in a diffuse pattern within the brain parenchyma for up to 4 and 24 h, indicating that DNZ-NLP passes the BBB but at a lower rate

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This precise regulation of chemotactic response prolongs the intensity and duration of local immune reactions, thereby exacerbating melanocyte destruction (104)

In general, some patients report benefits lasting from 6 months up to a year or more, especially with ongoing supportive care and rehabilitation

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