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Activation of the intrinsic coagulation cascade leads to inappropriate thrombolytic events as well as resulting in increases in inflammatory cytokine release from leukocytes that are activated as a result of the pro-coagulant state

doi: 10.1016/j.lfs.2019.03.001 22 DAngeloS.ScafuroM.MeccarielloR

These risks are especially relevant at higher doses, when IGF-1 is stacked with other anabolic compounds, or when used without breaks between cycles

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Sinha, Deepankar K et al
