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73 Indeed, there is evidence suggesting that FGF21 can be expressed and secreted by the heart following cardiac damages such as cardiac hypertrophy, oxidative stress and MI, and exerts its diverse cardioprotective functions in an autocrine manner

The reason is relatively straightforward

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However, low-dose GABA over months failed to induce neogenesis of -cells from ductal tissue based on lineage-labelled ductal tissue in Sox9CreER;R26R yfp mice (68)

Consequently, the reliability of translating these preclinical results to clinical settings requires further verification
