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Here, it will be important to identify the structural features of CnoX chaperedoxins that allow them to transfer substrate proteins to GroEL/ES and to determine whether these features are found in other bacterial holdases
This idea was further supported when similar phenotypes were observed across ferroptosis-sensitive and ferroptosis-resistant cancer cell lines (Extended Data Fig

The NRF2 pathway is regarded as the most important system controlling antioxidant defense in vivo, which can resist oxidative stress damage

Some people eat enough B12 yet still struggle because the gut cannot absorb it well
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