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doi: 10.1093/jn/121.4.539 28

But, as a treatment of heart failure, L-C has not been recommended in patients with current or prior symptoms of heart failure with reduced ejection fraction and heart failure with preserved ejection fraction in the American guideline [3]

5 The newer NCI-CTCAEv4 was released in May 2009, and its most important difference when compared with version 3 is that NCI-CTCAEv4 harmonizes with the lowest level terms from the Medical Dictionary for Regulatory Activities (MedDRA), which are listed based on their MedDRA primary system organ class, eg, immune system disorders or nervous system disorders
[DOI] [PMC free article] [PubMed] [Google Scholar] 11.Aonso-Diego G., Krotter A., Garca-Prez

In two randomized, controlled trials on 889 women, 3 mg of drospirenone along with 0.020 mg ethinyl estradiol achieved total- or near-total clearance of acne scores in 18% of subjects compared to only 6% of subjects receiving a placebo (Tan 2007)
