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This mechanism has positioned AHK-Cu as a compound of interest for researchers studying skin matrix integrity, structural protein regulation, and age-related changes in connective tissue biology
They were able to replicate the negative correlation in murine models where miR-338-5p knockdown increased IL-6 expression [74]
10.3389/fphar.2019.00382 Front Pharmacol

Maiorino M, Scapin M, Ursini F, Biasolo M, Bosello V, Floh L (2003) Distinct promoters determine alternative transcription of gpx-4 into phospholipid-hydroperoxide glutathione peroxidase variants

they are research observations in laboratory models