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As expected, GHK-Cu decreased LPS-induced TNF- and IL-6 secretion, and suppressed phosphorylation of p38 MAPK and NF-B p65 (Supplementary Figure S2)

GHK-Cu influences gene expression patterns that are crucial for maintaining nervous system health
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These peptides primarily act through the GH/IGF-1 axis, which activates the PI3K/Akt/mTOR cascadestimulating satellite cell proliferation, muscle protein synthesis, and chondrocyte matrix production