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10.1007/s10162-012-0353-0 42 OuH

Compared to partial sciatic nerve ligation (pSNL), the CCI model demonstrates more pronounced effects in inducing mechanical allodynia, thermal hyperalgesia, and cold allodynia (4, 49, 50), and reliably elicits spontaneous pain-like behaviors (51, 52), along with fewer ectopic pain-like behaviors (53), typically within 1014 days post-surgery

Imagine throwing a dart

Furthermore, different organs have distinct copper ion requirements, further complicating the issue of tight copper regulation (181)
