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Despite these advances, mammalian cells require exogenous growth factors, hormones, and complex macromolecules for survival and proliferation (Dos Reis et al., 2022

1 Introduction Parkinsons disease (PD) is the most common movement disorder and the second most prevalent neurodegenerative disease ( Given the incomplete understanding of PDs underlying pathological mechanisms, current therapeutic strategies primarily offer symptomatic relief rather than halting disease progression

[DOI] [PMC free article] [PubMed] [Google Scholar] 208.Chen J.M., Yang Y.P., Chen D.Y., Han J., Jin X.Y., Huang Z.X., Xu C.B., Shen Y.M

Interestingly, thermosensitive hydrogels can effectively increase drug bioavailability after nasal delivery

doi: 10.1002/smll.200500527