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doi: 10.3389/fnbeh.2019.00123 173 ClarkeGGrenhamSScullyPFitzgeraldPMoloneyRDShanahanFet al
Interestingly, plasma concentrations of the indoles synthesized from TRP, I3AA, and I3PA, were found to be significantly increased in the MDD patients in this study after the SSRI treatment

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clinical use typically runs 1226 weeks and is supported up to 52 weeks under medical supervision [3]
Subcutaneous injection offers bioavailability of approximately 15-20% based on animal data, while intramuscular administration may provide 45-50% bioavailability in some species