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Y-hG: Investigation, Writing original draft
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In addition to the primary research articles, there were 14 reviews on the topic that proved useful for background evidence [1,3,59,60,61,62,63,64,65,66,67,68,69,70]
The potential side effects would be the same regardless of which form of methotrexate you take
Depletion of intracellular glutathione (GSH) markedly promotes mitochondrial ROS production and triggers mitochondrial membrane depolarization (Lohan et al., 2018)
