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Future work should focus on defining riboflavin-responsive endophenotypes, validating combination treatment paradigms, and establishing robust clinical frameworks to integrate riboflavin into personalized neurotherapeutic regimens

v It took Searle, the manufacturer, 16 years to get aspartame approved as a food additive in the United States, and they were under investigation for performing fraudulent studies

Schultz ST, Klonoff-Cohen HS, Wingard DL, Akshoomoff NA, Macera CA, Ji M

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In coronavirus-related cases, SARS-CoV-2 infection negatively regulates the abundance of ACE2 on cell surfaces, as suggested by evidence [41]