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doi: 10.1002/jbt.23096

188,195 HSP40 hypo-expression has been observed in ovarian cancer lesions resistant to paclitaxel, topotecan, and cisplatin

doi: 10.1038/nature17940

Exploiting this vulnerability has led to the development of PARP inhibitors, which selectively target cancer cells with impaired DNA repair pathways
748750 Penicillin-binding protein (PBP)-type thioesterases (TE) have been mined and applied towards the generation of large libraries of macrocycles
