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Clinical translation requires human CSF pharmacokinetic assays to prove BBB bypass, a rigorous dose-escalation Phase I trial to establish a safe human NOAEL for chronic dosing, and an RCT utilizing precise neurocognitive testing (e.g., MoCA) to confirm that murine transcriptomic shifts yield functional neuroprotection in humans

Roles of insulin-like growth factor-I and growth hormone in mediating insulin resistance in acromegaly

This spatial organization suggests that the site of ferroptosis initiation may depend not only on where lipid peroxidation first arises but also on where CoQ 10 is available and efficiently maintained in its reduced state

Although [1- 13 C]DHA and [1- 11 C]DHA are chemically and biochemically equivalent, the techniques used to study them in vivo are considerably different

previously called nonalcoholic fatty liver disease [NAFLD]