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Description
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[7] Cleveland Clinic

Salter AM, Fisher SC, Brindley DN: Binding of low-density lipoprotein to monolayer cultures of rat hepatocytes is increased by insulin and decreased by dexamethasone

Patients treated with those two drugs should be carefully monitored for signs and symptoms of hyperammonemic encephalopathy

Interestingly, simultaneous deletion of FOXO1 and TSC1 from livers lacking AKT completely restored lipogenesis in vivo , independent of increased Insig2a expression, indicating that the AKT-FOXO1 signaling axis may additionally regulate DNL (325)
