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Shuttles copper into cells through receptor-mediated and passive pathways, stabilizing copper in a redox-controlled form

Thus, AC-induced apoptosis is largely mediated through the homeodomain-interacting protein kinase 2 (HIPK2)-p53 pathway augmentation (Zhou et al

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Consequently, there is an increasing emphasis on incorporating advanced, human-relevant models, such as organoids and organ-on-a-chip (OoC) systems to generate more predictive and translational data for future research into CQDs [86, 175]