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It is indicated for treating vitaminB12 deficiency in conditions such as pernicious anemia, dietary deficiency, and malabsorption syndromes, as well as for use in diagnostic procedures like the Schilling test

Dietary sources of Vitamin B12 include animal products like meat, poultry, fish, dairy, and oral supplements

Studies also show that giving exogenous melatonin to animals also increases survival time in a similar manner to calorie restriction.[ref] Not all studies show this, so it may be species-specific

however, it may have an adverse effect on liver fat metabolism and increased blood clot risk

For instance, one aesthetic doctor might use GHK-Cu alongside antioxidants and retinoids in a skin improvement regimen