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[DOI] [PMC free article] [PubMed] [Google Scholar] 168.Franceschi C & Campisi J Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases

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For those without an absorption problem, research suggests that high-dose oral B12 supplements can be as effective as injections in raising and maintaining B12 levels

Smoking: Tobacco use can lead to black spots on the tongue due to the buildup of tar and nicotine

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