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CD38 deficiency delayed cell senescence by inhibiting the generation and secretion of senescence-associated small extracellular vesicles (SA-sEVs) Evidence has indicated that small extracellular vesicles (sEVs), including exosomes, facilitate neighboring nondamaged cell senescence via a bystander effect
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As people age, they sometimes have trouble absorbing vitamin B12, even when taking pills by mouth, which is when vitamin B12 injections may be considered

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As you get older, your body naturally produces less NAD+