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Agladoglu SY, Cetnkaya S, Savas Erdeve S, Onder A, Kendrc HNP, Bas VN, Aycan Z

A higher pre-drug urinary level of the compound taurine was associated with a lower degree of hepatotoxicity, whereas a higher pre-drug level of trimethylamine-N-oxide and betaine was associated with a greater severity of liver damage

(Zhang et al., 2013a)

Wakatsuki A, Okatani Y, Ikenoue N, Izumiya C, Kaneda C

Substantial improvement was also achieved in some of the patients in group C who were received HQ cream, but the fading of melasma lesions was reversible after discontinuation of treatment in HQ receiving group
