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Fusco G, Chen SW, Williamson PTF, Cascella R, Perni M, Jarvis JA, Cecchi C, Vendruscolo M, Chiti F, Cremades N, Ying L, Dobson CM, De Simone A (2017) Structural basis of membrane disruption and cellular toxicity by -synuclein oligomers

Limited proteolysis, which results in the accumulation of specific fragments corresponding to the more rigid parts of a protein, is different from the total proteolysis (also through the action of proteases) leading to the complete or near-complete degradation of a protein into its constituent amino acids, which is useful for determination of amino acid sequence

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