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Oxid Med Cell Longev (2017) 2017:1202459

In the study Increased intake of calcium reverses vitamin B12 malabsorption induced by metformin , it was found that providing calcium supplementation to people taking metformin, was able to help prevent metformin-induced vitamin B12 deficiency

Environmental enteric dysfunction induces regulatory T cells that inhibit local CD4 + T cell responses and impair oral vaccine efficacy

Zhang J, Hu W, Wang P, Ding Y, Wang H, Kang X

Firstly, we detected the expression and location of FOXO4 in mice testes by immunohistochemical staining and found that FOXO4 was rarely expressed in young mice testes, but expressed typically in the Leydig cells of aged mice (Figure 6A)