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Description
The polyunsaturated nature of PUFAs enables critical signaling and membrane fluidity functions while conferring peroxidation susceptibility, rendering membranes rich in PUFA-phospholipids-synthesized by ACSL4 and LPCAT3-vulnerable to ferroptosis through iron-catalyzed Fenton reaction-mediated oxidation (116)
81 Measurement of two alcohol metabolites, phosphatidylethanol and ethyl glucuronide, also shows promise as an innovative way to detect recent alcohol use
A master regulator of alpha-synuclein aggregation
These results demonstrate that Mrp2-deficient organism is more sensitive to estrogen-induced cholestasis
Interestingly, individuals with DM1 exhibit lower plasma concentrations and decreased activity of A1AT compared to other people (107)
