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doi: 10.3233/JAD-2010-091672

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The identification and confirmation of a highly effective, balanced dual incretin agonist enables a more physiological approach to treating conditions associated with impaired glucose tolerance [78]

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Without formal reproductive toxicity studies following OECD Test Guideline 414 (prenatal developmental toxicity) and 416 (two-generation reproduction toxicity), we are operating without the data that regulatory science requires before concluding a compound is safe for use during conception attempts or pregnancy

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Part II: Guidelines for Recreational Water Quality C.1 The overall approach The principle of using guideline values is simple: we measure the level of faecal indicator organisms, which do not necessarily cause disease themselves but signal the potential presence of disease-causing organisms

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The key is coordinating the IPR timeline with the ANDA prosecution to ensure that a favorable PTAB decision can be translated into earlier approval and launch, rather than simply establishing invalidity after the commercial window has closed

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