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Poquette NM, Gu X, Lee SO

In 2002, a randomized, double-blind study (N = 333 LOE1b) showed that LC supplementation improved neurophysiological parameters and significantly reduced pain in patients with diabetic PNSDs [72]

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The recent implementation of more defined clinical and histological criteria, with the development of dermoscopy and computer technology, has led to early detection of melanomas and possibly contributed to the increased incidence of diagnosis (annual increase of 2.7% between 1986 and 2007).(1) However, the misdiagnosis of melanomas (overcalling and undercalling) has also played a significant role in this regard, especially since melanomas can mimic a variety of other benign and malignant neoplasms

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