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As mentioned above, GSH is synthesized only in the cytoplasmic matrix, but it is also found in intracellular organelles, including the mitochondria, nucleus, and endoplasmic reticulum

however, since research studies conducted on the cross talk between EpCAM and the RAS/RAF/MEK/ERK cascade have been limited to recent years and even sometimes are conflicting, it is almost impossible to define a conclusive opinion regarding the cross talk between c-Met and EpCAM through this pathway (Fig

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The interaction with eNOS and COX2 gene expression, and counteraction of the aggravation effect of the NOS-blocker, L-NAME [38], might suggest that NO system function might be accordingly recovered