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In vitro drug screens are performed on either cell-free protein aggregates, animal-derived cell lines, or patient-derived motor neurons [7, 197]

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PMID: 34540726

Research has found that the role of gut microbiota in peripheral anti infection may also depend on agonists of Toll receptors and NOD like receptors entering the body from the gut

4.4.2 Mechanism of action in dry eye disease A causal relationship exists between oxidative stress and mitochondrial dysfunction, as the copious amount of free radicals produced by oxidative stress can cause damage to mitochondrial complex I