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(PubMed) Marti-Carvajal AJ, Valli C, Marti-Amarista CE, Sola I, Marti-Fabregas J, Bonfill Cosp X

Chen et al., 2011)

Combined, these findings highlight the critical role of iron and ferritin in regulating the proliferation and invasion of CSCs in brain tumors, demonstrating that, depending on the availability of the LIP, CSCs modulate their cellular fate

Drug transport and metabolism Various trans-membranous proteins such as ABC have been well reported for the resistance initiation against several chemotherapeutic drugs

However, it can become pathogenic when its environment is disrupted, leading to biofilm formation