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It showed significant anti-MERS-COV activity (SI = 12.1)

121 One crucial signaling pathway activated by mechanical stress is the MAPK/ERK pathway

Temperature excursions denature the compound irreversibly

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One in vivo comparison of GHK versus GHK-Cu in rat experimental wounds found that GHK alone had no effect, and only the copper-bound GHK-Cu form produced a statistically significant increase in collagen accumulation evidence that the copper ion itself, not the peptide backbone alone, may be responsible for much of the collagen-stimulating activity