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Polycythemia vera has also been reported with parenteral methylcobalamin

More serious B12 deficiencies have the potential to impair heart and neurological function, leading to a wide range of serious symptoms, including but not limited to tinnitus, severe joint pain, memory problems, depression, anxiety, poor muscle function, ataxia and changes in reflexes

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In laboratory settings, AOD9604 may be used to investigate pathways related to lipid turnover, cellular energy regulation, and adipose tissue signaling

Therefore, monitoring of the platelet count and serum potassium concentrations are recommended during therapy